Keeping your dog healthy isn’t just about food and exercise—supplements can play a key role, especially as your dog ages or faces specific health issues. With dozens of options on the market, we cut through the noise and rounded up the four best dog vitamins and supplements in 2025, based on veterinary guidance.
1. Nutra Thrive for Dogs
Best for: Overall health and vitality
Our Rating
Comfort 5/5 Effectiveness 5/5 Convenience 4.9/5 Value 5/5
Nutra Thrive is a go-to for many vets because it covers all the bases: digestion, immunity, energy, and coat health. It’s a powdered supplement packed with probiotics, enzymes, vitamins, minerals, and antioxidants. If you’re looking for a single product to give your dog a full health boost, this is it. Especially helpful for dogs with low energy, frequent stomach upset, or dull coats.
2. Pet Honesty Multivitamin 10-in-1
Best for: Daily all-in-one support
This chewable multivitamin is ideal for dogs of all ages. It includes glucosamine for joint support, omega fatty acids for skin and coat, probiotics for gut health, and vitamins A, C, and D. It’s tasty enough that most dogs take it like a treat. Vets like this one for its balance—it doesn’t overdo any one area and works well for general maintenance.
3. Nutramax Cosequin DS Plus MSM
Best for: Joint health and mobility
Older dogs or active breeds can benefit big from joint support. Cosequin DS is one of the most trusted supplements in this category. It combines glucosamine, chondroitin, and MSM to protect cartilage and reduce inflammation. It’s especially helpful for dogs with arthritis or signs of stiffness. Many vets recommend starting it even before issues show up as a preventative.
4. Nutramax Denamarin
Best for: Liver health
If your dog has liver issues or is on long-term medication, Denamarin is a top vet pick. It includes SAMe and silybin (from milk thistle) to help protect liver cells and improve function. It’s not a general supplement—it’s targeted—but for dogs that need liver support, it’s one of the best options out there.
Final Thoughts
Every dog is different. What works for one might not be right for another. Before starting any supplement, check with your vet to make sure it’s a good fit for your dog’s health history and needs. But if you’re looking for trusted, 2025-approved options, these four are a solid place to start.
